Louisville, Kentucky

Our flagship Accelerator is hosted in our headquarters in the heart of Louisville, KY.

Louisville is a strategically positioned national hub of healthcare heritage, knowledge and innovation. It is the birthplace and growing ground of healthcare behemoths such as Humana to successful startups such as Apellis and is home to a multitude of top-tier aging care organizations and research universities.

The startup ecosystem in Louisville is a supportive environment for entrepreneurs to launch in a system rich in resources for support and mentorship, all in a centrally located geography where living is affordable.

Important Dates

Bootcamp Dates:  Aug 3, 2022 – Oct 21, 2022

Demo Day: October 20, 2022

Location: Virtual via Zoom


Register for Demo Day here!


Greg Langdon

Greg’s background is in corporate and product strategy for technology businesses. He has experience in executive management, business development, marketing and public relations, acquisitions, product management, software architecture and development, project management and digital electronics design.

Jacqueline L. Wood

Jacqueline is a visionary and strategic forward healthcare executive. She has a strong background in business development, strategic planning and increasing efficiencies throughout the healthcare continuum. Her ability to challenge the status quo gives her a unique approach to today’s healthcare issues. Jacqueline is a proven leader and has an affinity to bring teams together to maximize collaboration. Her strong clinical and business background helps her to assist others in operations, entrepreneur ventures, business development or consumer engagement.

Jake Miller

Jake has over 18 years experience designing, developing, and implementing new products, services, and business models. Professional focus is on making entrepreneurial endeavors a reality for enterprises of all sizes. Recent professional highlights include introducing a first-of-its-kind retail-health clinical trial model and leading the cross-functional launch of 11 new products in less than 18 months in a highly-matrixed organization.

Rebecca Brown Rice

Rebecca is the Director of Product at Render Capital.  Previously, Rebecca was the Director of Operations at the Louisville Healthcare CEO Council (LHCC) and prior to that, Rebecca managed the NIH-REACH Hub and its associated healthcare technology development grant at the University of Louisville (called ExCITE) where she oversaw the investment of $3million into a portfolio of 19 promising early-stage healthcare technologies, including small molecule therapeutics, diagnostics, mHealth technologies, and direct-to-consumer products. Rebecca received her BS in Neuroscience from Brown University and is a PhD candidate in Neuroscience at Yale University.

Bob Saunders

Bob is a General Partner of OCA Ventures (Chicago), a Founding Partner of Saunders Murdoch and Associates (Louisville/Boston), and is an active investor in many healthcare startups. Bob was a Managing Director and General Partner at Chrysalis Ventures from 1997 to 2009. Bob was a founding board member of MetaCyte Business Lab, the University of Louisville’s life science incubator. Over the last 30 years, he has invested in several dozen startup companies and has mentored 100+ startups. Bob received a B.A. from Stanford University, an M.Sc. from the London School of Economics, and an M.A. from Harvard University. He was both a Fulbright Scholar and a Marshall Scholar

Jackie Willmot

Jackie has 30+ years of experience in the healthcare industry including 13 years as a clinician and 15 years as an executive at Humana in the Innovation Center including 3 years working for a Humana Startup in the United Kingdom. Since leaving Humana in 2009 Jackie was trained by Steve Blank in his ‘Lean Launchpad Educators Class’ at Stanford University, has worked with 300+ startups, and serves as a business coach in a variety of capacities. She was a founding member and on the Board of Directors of the Network for Entrepreneurial Women and has worked with healthcare startups via the LaunchIt program where she works closely with Coulter, ExCITE, and I-Corps funded companies. Jackie is a Principal Investigator (PI) on an NIH funded initiative to create the XLeratorNetwork in the Southeast IDeA States and also sits on the External Review Board (ERB) for the NIH funded KYNETIC program, the University of Kentucky’s External Advisory Committee (EAC) for the NIH funded CCTS program, and the Review Panel for the Puerto Rico Science, Technology & Research Trust’s BioTech Accelerator Program “EnTRUST”. She is a Master’s prepared Perinatal Clinical Nurse Specialist and holds an MBA from the University of Louisville’s entrepreneurship program, a Master’s of Science from the University of Pittsburgh, and a Baccalaureate Nursing degree from Villa Maria College.

Eugene Krentsel

Prior to joining XLerateHealth, Dr. Krentsel served as Associate Vice President for Research and Innovation and Adjunct Professor of Entrepreneurship at the University of Louisville. He was responsible for the full range of activities in the discovery-innovation-translation-commercialization spectrum at UofL, including working with external groups in the public and private sectors to promote commercialization of university technologies and advancing industry engagement and entrepreneurship. Prior to being recruited to UofL in 2013, he served as Assistant Vice President for Entrepreneurship and Innovation Partnerships at Binghamton University in New York, where he helped develop and protect faculty intellectual property, paired researchers’ expertise with pressing market needs, and offered guidance to faculty and students interested in starting their own business. Eugene is a member of the National Science Foundation’s Advisory Committee on SBIR.

Natalie Thurston

Natalie is the Program Director for the XLeratorNetwork and has over two decades of reimbursement experience – working for both a large national health plan and for a national provider of molecular diagnostic laboratory services. For the large national insurance company, she managed a team of clinicians responsible for guiding members to a National Transplant Network and implemented a novel clinical program of nurse navigation for patients. During this time, Natalie developed a comprehensive understanding of insurance operations from claim submission through appeals and payment. Natalie’s experience with large payers enabled her to help life science startups develop their reimbursement strategy and obtain positive coverage decisions for products from both commercial and government payers e.g. Medicare and Medicaid. Natalie received a Bachelor’s in Nursing from Indiana University in Indianapolis and a Master’s in Business Administration from Indiana University Southeast. She also maintains a certification in Healthcare Quality (CPHQ).

Sebastian Alvim

Prior to stepping into the role of Managing Director, Sebastian joined the XLH team in Flint as Program Director and was instrumental in launching XLH’s 2nd location in Flint — which included collaborating with multiple healthcare stakeholders and investors in the region, building out and enhancing the programming, and creating technology tools that have improved the efficiencies and effectiveness of running the accelerator.   Sebastian has extensive experience with evaluation of business strategy, commercial viability, and market analysis. He has advised 50+ healthcare startup companies successfully applying Lean Startup Methodology to help them develop, grow, and scale up their businesses.   Sebastian also serves as a startup judge for the Michigan startup competition Invest360.  Prior to XLH, he was a Co-founder of MyNurse, a home healthcare marketplace for caregivers and patients. Sebastian began his career at a British consultancy multinational firm, where he was responsible for human resource operations and strategic corporate advisory work (including change management, restructuring, and organizational assessment).  

Karen Handmaker

Karen is an engaging population health management expert with a passion for new models and technologies to improve health and healthcare with the “consumer at the center.” Over the course of her career, Karen has worked at major healthcare and benefits consulting firms as well as technology and service companies delivering disease management, wellness and population health programs to employers, health plans and health systems. Karen received a BA in American Studies at Trinity College in Hartford, CT (Phi Beta Kappa) and her Master in Public Policy from Harvard University.

Ashok Seetharam

Ashok is the co-founder and COO of PAXAFE, an AI enabled supply chain technology startup that provides end-to-end real time visibility for B2B shipments. Prior to PAXAFE he co-founded two healthcare startups and served as it’s CTO for 4+ years. Ashok has experience in user-centric design, hardware/software product development, CAD/CAM, 3D printing, regulatory and supply chain and holds several patents in the healthcare space. He currently serves as an Entrepreneur in Residence at the Economic Growth Institute, University of Michigan and also as a mentor and coach at gener8tor and XLerateHealth accelerator programs.