XLH Mentors


  VRTogether (Lexington, KY) – VRTogether reduces social isolation and loneliness in senior citizens through an evidence-based virtual reality platform. The technology provides an effective… Read More »VRTogether

Urban Docz

Urban Docz (Detroit, MI) is a simple, secure, and affordable telehealth platform that provides virtual healthcare access to women in underserved and low-income communities, starting with… Read More »Urban Docz


InterJad (Southfield, MI) is developing an interactive, clinical research training platform for healthcare professionals that utilizes a unique combination of web and mobile-based gamified simulation.… Read More »InterJad

Hodos Health

Hodos Health (Detroit, MI) is a digital health company that helps medical practices and community health centers optimize operations, improve clinical staff utilization and patient outcomes,… Read More »Hodos Health


Coordinista (Kalamazoo, MI) Designed by clinicians for clinicians, Coordinista is a digital health startup that gives providers the tools they need for effective care delivery at… Read More »Coordinista


Lealtà (Atlanta, GA) – Developed by a clinician executive, Lealtà is a SaaS company focused on driving patient loyalty in healthcare and hospital systems. The average… Read More »Lealta


Kinometrix (Fort Belvoir, VA) – Hospital-acquired conditions (HACs) harm patients and cost US hospitals $98 billion annually. Kinometrix is on a mission to eliminate HACs… Read More »Kinometrix


Ensofy (Tbilisi, Georgia) – Led by experienced AI and healthtech founders, Ensofy has developed VoiceAI, an AI-enabled screening and monitoring tool for major depressive disorder… Read More »Ensofy


Constance (Westport, CT) – Constance is a surgical clinical decision support platform maximizing the ability to prescribe, quantify and stratify peri-operative risk. The Constance state-of-the-art… Read More »Constance

Biosphere Lab

Biosphere Lab (Louisville, KY) – Biosphere Lab is a veterinary diagnostic laboratory with a particular focus on rare and exotic animals. Biosphere provides anatomic pathology… Read More »Biosphere Lab


Bainom (San Francisco, CA) – Bainom is an AI and machine learning based platform that matches genetic data with up-to-date information from hundreds of scientific… Read More »Bainom

Atalan Tech

Atalan Tech (Boston, MA) – Started by Harvard, Yale and Oxford researchers and graduate students, Atalan has developed a customized clinician wellness risk management software… Read More »Atalan Tech


TremBlock (Plantation, FL) is a unique mouthguard targeted for use in patients with epilepsy or other known seizure disorders. The device is capable of dispensing… Read More »TremBlock


ModoScript (Boston, MA) is a digital health company that provides remote monitoring of rigorous treatment protocols in oral oncology and other chronic conditions that require… Read More »ModoScript


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iMama (Raleigh, NC) is a digital health platform using artificial intelligence to help mothers prolong their breastfeeding cycle and help employers to provide nursing moms… Read More »iMama


20Lighter (Tampa, FL) is a unique program that targets visceral fat and dietary inflammation to support patients who are ineligible for a surgical procedure or… Read More »20Lighter

Vern Health

Vern Health (East Lansing, MI) detects emotions in communication in real time to support telehealth, customer service, and more. Vern Health utilizes proprietary AI diagnostic… Read More »Vern Health


MyHelse™ (North Beach, MD) is a customizable Platform as a Service that leverages data and analytics to identify early risks at both the individual and… Read More »MyHelse™

Isaab Innovations

Isaab Innovations (Flint, MI) is a physician-founded medical device company that has innovated a patent protected syringe that improves medication delivery. MultiFlow syringe incorporates the… Read More »Isaab Innovations


DRS.LINQ (Newton, PA) is creating a virtual cardiology office to enable enhanced connectivity between the patient and physician through proprietary vEKG and the mHeart App… Read More »DRS.LINQ


Adlore™ (Kalamazoo, MI) is designing a next generation device for the treatment of lower extremity wounds, including diabetic/neuropathic foot ulcers, venous stasis leg wounds, arterial… Read More »Adlore


SmartBreast Corporation (Mars, PA) has developed a cutting-edge medical scanner called SmartBreast™ that aims to save lives, reduce cost, and mitigate suffering through early breast… Read More »SmartBreast


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LockUpLead neutralizes the CDC’s #1 environmental neurotoxin in homes, schools, and urban soil – poisonous lead. The permanent brain damage to young children that leads to learning and… Read More »LockUpLead


NeuroAtlas (Louisville, KY) developed medical software that utilized non-contrast MR imaging to detect and develop comprehensive analyses neurological disorders. Initial focus was in the field… Read More »NeuroAtlas

Cancer University

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Cancer U is an online membership platform for cancer patients and cancer caregivers to educate and empower them to become advocates for themselves during their cancer journey to improve outcomes and reduce costs.


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MDHealthtrak tracks disease symptoms, facilitates communication for both patients and doctors, and can even manage patient appointments.

IBIS Therapeutics

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IBIS Therapeutics (Tampa, FL) tackles the problem of therapeutic efficacy using a unique AI engine capable of predicting absorption, distribution, metabolism, excretion and toxicity to identify the best drug candidates from a quarter billion small molecules. IBIS’s first to market product will focus on COVID-19 and inflammation which enables a cost-effective drug discovery process to investigate every protein in the SARS-CoV-2 viral proteome for drug candidates in a few months compared to the time required for traditional compound discovery.


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2innovate (Metamora, MI) specializes in the creation of innovative medical devices, including PeriTect™ and Windsor Gait Assist™. Their latest product, Windsor Gait Assist™, is the first-ever cost-effective traveling “seat belt” for the elderly and disabled that significantly reduces the risk of serious injuries from falls on stairs and level surfaces in hospital and home settings.


Vivorte (Louisville, KY) is a medical device company that is commercializing two innovative orthopedic devices: a minimally invasive implantable device designed to reduce hip fractures and save lives, and a synthetic/biologic bone void filler that is strong and remodels quickly.

Trajectory Healthcare

Trajectory Healthcare (Loveland, OH) is a population health analytics solutions company that helps evaluate, improve and design population health management programs. Using its patented analytics engine and easy to use software, Trajectory transforms how customers see and manage their population health data, helping them make better clinical and financial decisions.

Toggle Health

Founded in 2016, Toggle Health is a healthcare technology company with the goal of delivering a breakthrough surgical user experience in the operating room. Toggle Health connects surgeons to their digital case data in the sterile field of the operating room.


Thrive365 is the only patented nutritional meal scoring platform proven to benefit individuals living with Type 2 Diabetes and Pre-Diabetes. Our proprietary platform combines the best of nutritional science, world class technologies and “Win the Day” health coaching.

TheraB Medical

TheraB Medical (Lansing, MI) has created the first completely portable and wearable 360 degree phototherapy treatment for infant jaundice called SnugLit. Over 60% of babies are born with jaundice but current treatment methods require continual supervision that impedes parental bonding and increases undue stress for the family.

Thaddeus Medical Systems

Thaddeus Medical Systems (Rochester, MN) improves healthcare outcomes by tracking, protecting and documenting temperature-sensitive products and specimens through the supply chain. Solutions bridge the gap between price, quality and perception of value within cold chain packaging.


Telasight (Louisville, KY) is a telehealth company providing real-time practitioner to practitioner consults via phone, video-conference, text and email. When a patient is sitting in a provider’s chair with an unfamiliar or uncommon condition, a practitioner can now get a real-time consultation from an up-to-date expert in their field to receive the current standard of care and determine the best treatment and management plan.

Stonestreet One

Stonestreet One (Louisville, KY) (acquired by Qualcomm) provides software solutions for Bluetooth wireless technology and has developed several healthcare and other IoT applications.  The company was… Read More »Stonestreet One

Seikowave Dental

Seikowave Dental (Lexington, KY) using optics similar to those found in digital cameras, Seikowave dental’s 3D imaging platform enables dentists to make immediate intra-oral 3D measurements of patient’s teeth versus the traditional method of making dental impressions and molds.


SafetyCo (Detroit, MI) offers a hospital-developed technology that decreases the risk of patient injury while therapists perform physical therapy at the bedside. Their device, SafetySit, decreases the need for multiple caregivers at the bedside and increases the safety for both the patient and therapist.


RxLightning (New Albany, IN) digitizes, automates and streamlines the historically complicated manual enrollment process of starting a patient on specialty medications. Specialty medications are expected to account for 70% of new medication launches through 2023. With RxLightning, healthcare providers can quickly and easily complete the enrollment process for every specialty medication in every therapeutic area, helping reduce paperwork, streamline communication, and accelerate the speed of therapy for patients.


Repaytient (Louisville, KY) provides interest and fee-free payment plans to help hospital and clinic patients pay their rising out-of-pocket expenses. They permit these payments to be made over time, which allows patients to receive essential and elective medical care. This ensures patients have the care they need and provides increased cash flow to healthcare facilities and clinics.

RCM Brain

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RCM Brain (Louisville, KY) Revenue Cycle Management is an AI driven revenue cycle workflow automation platform that makes claims processing staff 3 to 10 times more productive. It uses artificially intelligent workflow bots to connect data and execute tasks across legacy billing systems, clearinghouses, and payer websites.

Progentec Diagnostics

Progentec Diagnostics (Oklahoma City, OK) Progentec’s biomarker-based platform offers multiple tests to manage various facets of Lupus ranging from diagnosis to disease tracking and flare prediction – these come with a suite of digital health solutions.

Prodigy Biosciences

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Prodigy Biosciences (Louisville, KY) has developed a personalized, innovative approach to food testing and allergy management. Prodigy’s immunoassay can specifically detect traces of allergens such as peanuts (a top food allergen) that can be used for a rapid lab analysis.


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Personal Medicine Plus is a mobile health platform addressing underserved Medicaid and rural populations. The software app is designed to help people with chronic conditions such… Read More »PreventScripts

Pahoola Video Networks

Pahoola (St.Louis, MO) is a patient education company that produces and distributes high quality, engaging video content to educate patients and family members about medical procedures before, during and after their hospital visit. A more educated and engaged patient results in improved outcomes and patient satisfaction while reducing post-discharge readmissions.


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Orthopedix (Providence, RI) is a 3D-printed orthopedic implant company that creates personalized, patient-specific implants throughout the body. The implants are individually sized and shaped to fit to each patient’s unique anatomy, offering benefits not achievable with “off-the-shelf” orthopedic implants.

OR Link

OR Link (Lexington, KY)  is a mobile healthcare software company focused on redefining communication in and around the operating room. At its core, the unique software platform aims to simplify the process by which a surgeon’s “preferences” are stored, shared, and utilized in real-time between all the personnel in the OR.


OpenMarkets (Chicago, IL) is a service and technology company that creates visibility into the capital equipment purchasing needs for hundreds of hospital clients, letting the company match realtime needs and create volume-leveraged savings opportunities.

Occam Design

Occam Design (Louisville, KY) is the innovative leader in rapid, cost effective, regulatory complaint medical device development, including services for regulatory clearance and manufacturing. Their expert engineers, quality and regulatory professionals coupled with comprehensive manufacturing capabilities provide innovative and reliable solutions to the most challenging applications.

NX Prenatal

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NX Prenatal (Louisville, KY) NX Prenatal is developing novel assays and noninvasive early warning systems to detect subtle molecular changes in the maternal-fetal environment, with the goal of identifying pregnancies at risk for preterm birth and ultimately improving the rate of healthy pregnancy outcomes.

NX PharmaGen

NX PharmaGen (Louisville, KY) is developing molecular diagnostic tests for prenatal and oncology indications utilizing blood-based exosomal proteomics. Its NeXosome TM assays permit the early identification of pregnant women at-risk for preterm birth, as well as the time series evaluation of the molecular machinery of a tumor throughout the disease cycle.

NX Development Corp

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NX Development Corp (Louisville, KY) has developed the first and only FDA-approved optical imaging agent indicated in patients with high-grade gliomas (suspected World Health Organization Grades III or IV on preoperative imaging) as an adjunct for the visualization of malignant tissue during surgery. The company exited in 2018 in a sale to SBI Pharma Co Ltd of Japan.